Field: Mental Health
This 20-year chart of depression diagnoses shows an incredible shift
People are being diagnosed with depression earlier than in the past because of a decrease in stigma and better diagnostic guidelines.
Mathematicians suggest the “37% rule” for life’s biggest decisions
Mathematicians tell us that, to maximize the chances of the best outcome, we ought to ditch the first 37% of any options.
New kind of schizophrenia drug aces human trial
KarXT, a new schizophrenia treatment that addresses a wider range of symptoms than existing meds, has aced a phase 3 trial.
The Biden administration is preparing for legal psychedelics within two years
The Biden administration’s Department of Health and Human Services has sent a memo supportive of psychedelic therapies. What does that mean for the field?
ADHD drugs might also treat Alzheimer’s disease
Scientists reviewed 40 years of clinical studies that assessed the effects of NA-targeting drugs, such as certain ADHD drugs, on Alzheimer’s.
How natural “short sleepers” thrive on 4 hours of sleep per night
Natural "short sleepers" thrive on only four to six hours of sleep per night. Could their genetics explain why?
Your genes may impact psychedelic experiences
UNC researchers have found evidence that the genetic makeup of a crucial receptor may impact your psychedelic experience.
Widom of Daoism: why Yin-Yang is so much more than a tattoo
Yin-Yang symbolizes not a conflict or struggle but shows that nothing in life is solely either this or that.
Nurturing dads raise emotionally intelligent kids
Nurturing dads raise more emotionally intelligent children, helping make society more respectful and equitable.
The Four Enemies to a happy life and how to defeat them
Buddhist psychologists, Robert Thurman and Sharon Salzberg, have identified "Four Enemies" that are obstacles to a happy, fulfilled life.
The first FDA-approved clinical trial of psilocin has begun
“This has never been done before,” says Filament’s CEO.
Psychedelic research returns to Veterans Affairs
After decades, the Department of Veterans Affairs is once again investigating psychedelic therapies.
Two FDA-approved drugs may improve Alzheimer’s symptoms
A retrospective study found that Alzheimer’s symptoms improved in patients who took two FDA-approved drugs that treat psychiatric disorders.
Yale study of DMT for depression is encouraging
Yale researchers have conducted a small study finding DMT is safe and tolerable enough for more research.
Stimulating deep sleep may improve brain health, memory, and mood
Researchers are trying to harness deep sleep to bolster the glymphatic system, which helps flush brain tissue.
Geopsychology: Your personality depends on where you live
Scientists in the relatively new field of “geopsychology” are seeing links between personality and location.
Drug to treat alcoholism could also safely reduce anxiety
The alcoholism treatment disulfiram may be able to serve double-duty as an anti-anxiety medication, according to mouse studies.
AI maps psychedelic “trip” experiences to regions of the brain – opening new route to psychiatric treatments
To better understand how these effects manifest in the brain, we analyzed over 6,000 written testimonials of hallucinogenic experiences.
Video games for mental health are coming
New startup DeepWell Digital Therapeutics is developing video games to help treat mental health disorders.
Hugging a cushion that “breathes” can reduce anxiety
A study found that hugging a cushion that “breathes” was able to reduce anxiety for students prior to a test as much as guided meditation.
Brains scans of the placebo effect show new way to treat depression
A meta-study of placebo effect research has revealed a link between the phenomenon and brain stimulation as a depression treatment.
New antidepressant helps patients in just three days
Adding the new antidepressant zuranolone to standard treatments helped people with major depressive disorder feel better in less time.
Should psychedelics be patented?
The issue of patents has riven the psychedelic field. A lawyer’s repository of psychedelic info may make sure the new field stays fair.
Frontline healthcare workers are going to receive psilocybin therapy
University of Washington researchers are enrolling healthcare workers now in a psilocybin-assisted therapy study.
Psychedelics can change how you think about the universe
A new study finds that a single trip on a psychedelic can cause lasting changes in a person's metaphysical beliefs.
Psilocybin treatment relieves depression in largest trial yet
The largest psilocybin treatment trial to date suggests that the psychedelic drug can help people with treatment-resistant depression.
Cooling caps can help prevent chemo hair loss
Chemo hair loss is a common side effect for cancer patients, but cooling caps can help limit the loss.
Architects design new mental health facilities with healing in mind
Architects are incorporating neuroaesthetics insights into designs for medical facilities in an attempt to promote positive mental health.
Johns Hopkins receives the first NIH grant for clinical psychedelic research in half a century
For the first time in decades, the National Institutes of Health is funding a clinical psychedelic study, perhaps a turning point for the field.
Brain implant relieves woman’s treatment-resistant depression
A woman with severe treatment-resistant depression has found relief, thanks to “pacemaker” implanted in her brain by UCSF researchers.
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Just Might Work
Is DMT the best new treatment for depression?
Psychedelic therapy could bring the ancient healing powers of drugs like DMT into mental health clinics.
Can AI cameras predict suicide attempts at bridges?
Seoul is deploying an AI-powered camera system designed to predict suicide attempts at bridges and send rescuers to help people in distress.
Low doses of nitrous oxide may treat depression
A new, small study has found that low doses of nitrous oxide — laughing gas — can treat symptoms of depression.
A small dose of an ibogaine-like drug cures stress in mice
A novel drug designed like ibogaine but without the ibogaine trip or toxicity has corrected the effects of stress in mice.
Are we really addicted to technology?
Simplifying very complex things can lead to real harm.
Ketamine infusion: What it's like and how it works
Ketamine infusion therapy takes the anesthetic from dance floors to depression clinics. But how does the drug work, and what is it like?
MDMA for PTSD just crushed its phase 3 trial
Results from the first phase 3 trial of using MDMA for PTSD along with talk therapy found the drug to be effective.
Phase 2 trial finds psychedelic works as well as common drug
A small study has provided evidence of psilocybin for depression working as well as a popular SSRI.
Fireside Project is a support line for your bad trip
Fireside Project is a nonprofit that is providing a support line for your challenging psychedelic experiences — read: bad trip.
Can a blood test help diagnose depression?
An objective blood test could help provide a clearer understanding of the patient’s mental health.
Game triggers auditory hallucinations in mice and people
An experimental game that triggers auditory hallucinations in both mice and humans could lead to new treatments for schizophrenia.
Oral ketamine treatment reduced suicidal thoughts: Pilot study
A new, small study in Australia suggests that oral ketamine treatment may help treat suicidal thoughts.
Google trends reveal a boredom pandemic. How can we help?
Google trends showed that online searches for subjects linked to boredom and loneliness jumped dramatically, according to a study.
The best therapy dog may be a robot
A life-life robot dog might be an effective — or even preferable — alternative to a living therapy dog, according to a new study.
Tweaked psychedelic drug could treat addiction, depression
A modified ibogaine molecule could be a safer and more accessible treatment for addiction and depression than the psychedelic drug in its natural state.
Stopping nightmare disorder with a prescription-only watch
A prescription-only watch that treats nightmare disorder is the latest in a growing subset of health technologies called prescription digital therapeutics.
Psilocybin therapy appears to dramatically reduce depression
Psilocybin therapy — a combination of traditional therapy and supervised “trips” on the magic mushroom compound — shows promise as a depression treatment.
Teens create website to combat social isolation in seniors
To help combat the problem of social isolation, three Texas teens created Big & Mini, a website that sets up video chats between seniors and younger people.
App brings psychedelic-assisted therapy into your home
The Field Trip app aims to help people get some of the benefits of psychedelic-assisted therapy outside the confines of a clinic.
Remote therapy is as effective as face-to-face, for depression
The pandemic has therapists' couches off limits. A new study finds that remote therapy may be as effective for depression as face-to-face, so I gave it a try.
New algorithm gives trauma survivors a "PTSD risk score"
A newly developed algorithm calculates a "PTSD Risk Score" for people seeking treatment for traumatic injuries.
Can AI predict which depression treatment is most effective?
Artificial intelligence-powered algorithms that analyze brain scans are showing promise in helping doctors find an effective depression treatment on the first try.
Prescription video games for kids with ADHD could be on the horizon
With its FDA approval, EndeavorRx may mark the beginning of prescription video games for kids with ADHD and other mental health disorders.
MDMA has long-lasting benefits as a PTSD treatment
The benefits of MDMA therapy as a PTSD treatment appear to last for at least a year, according to a newly published paper.
Ketamine discovery may lead to new antidepressants
Researchers have uncovered new insights into how ketamine affects the brain, potentially illuminating the path to new antidepressants.
New health wearable measures sweat to track your mood
An app that works with a wearable wrist sensor to track how much a person sweats could change how we harness the power of biodata in the future.
The science behind your crazy pandemic dreams
If you’ve been having strange dreams and poor sleep during lockdown, you’re not alone. The anxiety-inducing pandemic, less activity, and more screen-time have many more people struggling with insomnia than usual.
The rise of virtual therapy
In a time when the need is great and the future is unknown, virtual mental health services like BetterHelp are bringing relief and hope.
Facing the fear of death in virtual reality
With a virtual reality death simulator, this immersive experience helps people address the uncomfortable subject of mortality and face their fear of dying.
Reading your digital signature to detect depression, Parkinson’s
Digital phenotyping uses our smartphones to detect anything from Parkinson's disease to mental health disorders.
Treating depression at home with a tDCS headset
At-home tDCS headsets are helping people treat their depression without having to go to a doctor’s office.
Could VR change how you trip on ketamine?
Virtual reality meets ketamine therapy to help treat pain, anxiety, and depression, to name a few.
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Dope Science
I use ketamine for depression – here’s how it works
Commonly known as a party drug, ketamine’s powerful effects on the brain have led doctors to further explore its medical potential. Now, the animal anesthetic is providing relief and hope for people with severe depression.
Scientists are developing brain implants that improve memory
New research sheds hope for sufferers of traumatic brain injury, Alzheimer’s, and for all of us, old age.
Improv for anxiety
In a judgement-free setting, improv requires the mind to focus on the present, providing natural anxiety relief for performers.
Psychedelic mushrooms explained
Psychedelic mushrooms, AKA magic mushrooms or psilocybin mushrooms, are currently being researched as a treatment for depression, addiction, and more.
Does playing sports quiet the brain?
Athletes across many sports have something in common - they can more easily “quiet” their brain to focus on what’s really going on.
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Catalysts
Rethinking addiction recovery with fitness
In partnership with Stand Together
As drug overdose deaths climb higher, this gym is challenging the thinking behind traditional models for addiction recovery services with free memberships open to anyone sober for at least 48 hours.
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Dope Science
Microdosing psychedelics
Microdosing is the no-flowers-in-your-hair practice of regularly taking minimal amounts of hallucinogenic substances. Although it’s currently illegal, millions of dollars are being poured into further research.
Ketamine explained: Understanding the special k drug
Ketamine, known recreationally as the “Special K” drug, is a trance-inducing anesthetic that researchers believe has more powerful uses off the dance floor.
Healing PTSD with MDMA therapy
New hope for PTSD sufferers is coming from an expected quarter: MDMA.
We may have found a drug to curb meth addiction
Meth addiction is on the rise, so this team of researchers is working to develop the first FDA-approved medication to treat the use disorder.
New promise for psychedelics and depression
New findings on psychedelics and depression show the benefits of microdosing, and could present more effective treatment options.
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Dope Science
Cannabis as a natural treatment for autism
When typical medications simply aren’t doing enough to manage their children’s symptoms, mothers like Jenni Mai are turning to medical marijuana. But with current regulations, parents are having to become pharmacists for their own families, and some are even moving across the country so they can legally access cannabis.
Nature is good for you. What about VR nature?
Nature has the power to reduce stress and enhance our moods. Can VR nature experiences be a substitute for physically spending time in the outdoors?
Diving deep into the brain to measure neurotransmitters
Researchers are taking the first measurements of neurotransmitters in active human brains, using computational psychiatry to understand how the mind works.
Marijuana and autism: Removing the stigma
Research is beginning to prove the hopeful connection between marijuana and autism treatment for symptom relief. Here is one man’s inspiring story.
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Through the Looking Glass
VR trips help treat depression in the elderly
In the U.S., about six million people over the age of 65 experience late life depression. So one organization is providing virtual reality excursions for seniors to help them experience life to the fullest.
Shedding the stigma of substance use
In partnership with Stand Together
By achieving fitness goals together, The Phoenix community is peeling off the shame, regret, and stigma often associated with addiction.
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Through the Looking Glass
Conquering fear with virtual reality exposure therapy
Whether a patient fears spiders or flying, VR technology allows therapists to treat anxiety disorders by simulating these experiences in a safe environment.
Advice from a death doula: unlocking life before death
Talking about death can actually make it a much less frightening topic. Here’s how working with a death doula or attending a local death cafe can help.
Addict-turned-neuroscientist on addiction and the brain
In our interview with neuroscientist Judith Grisel, she discusses the state of research on addiction and the brain, as well as society’s view of addicts.
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Catalysts
The mental health movement for Chicago’s inner city youth
In partnership with Stand Together
A remarkable transformation is taking place in several inner-city Chicago schools, and it's resulting in fewer gangs, drugs, and homicides. Could this new model of group therapy be the cause, and is it scalable?
Wilderness experience helps army vet adjust to life after war
Meet Thomas Weinheimer, an army veteran whose 53-day wilderness experience on a North Carolina trail helped ease his transition back to civilian life.
Wilderness therapy: A path to healing for Veterans
These long-distance treks use the power of nature over three to six months of exploration to help heal the invisible wounds of war, and the results are incredible.
This artist heals wounds of violence with tattoos
Brian Finn tattoos over scars from self-harm, violence, or human trafficking for free or at a discounted rate in order to help people heal.
Take a trip to Johns Hopkins' new psychedelic research center
Johns Hopkins is throwing its considerable clout behind the fast-growing field of psychedelic research, pouring $17 million into a research center to study the hallucinogenic drugs.
Scientists sidestep restrictions on cannabis research by taking their lab mobile
This mobile lab, run by scientists at the University of Colorado Boulder, is one of several workarounds developed...
Keeper of the missing
One woman is tracking thousands of missing people. Autism is her superpower.
Is the future of therapy… virtual? A look into virtual reality therapy
The immersive world of VR may have therapeutic benefits for people combating phobias, anxiety, and PTSD.
Is autism a mysterious medical condition or part of the spectrum of human diversity?
Rethinking Autism: Interview with NeuroTribes Author Steve Silberman
Can people with autism help create next-generation AI?
Daivergent is a new startup that hires people with autism to train artificial intelligence - and helps them start independent careers.
The joy of being wrong
In partnership with John Templeton Foundation
Can practicing intellectual humility make us smarter and happier? Science says yes.
These hero pups are helping veterans and prisoners heal
Hero Pups is an organization providing support dogs for military veterans and first responders. Now, prison inmates are helping train them - with great results.
Who will save your parent’s life story?
When her dad had Alzheimer’s, this journalist wrote his life story to help his caregivers understand him. Now, she’d doing the same for hundreds more.
Can cognitive behavioral therapy break the cycle of violence?
CBT is a promising way to reduce violence, so why has it been so hard to scale?
An app to help prevent suicide
Meet the teens who built the notOK App: a "panic button" for people who need help.
Personal genetics might solve the opioid crisis – and the pain crisis
Why does pain hurt more for some people? Why do others feel nothing at all?
Coffin-building club helps seniors face death and enjoy life
These seniors are tackling the stigma around death by decorating their own coffins.
Study shows schizophrenia begins in the womb, unraveling a genetic mystery
Half of genes linked to schizophrenia are primarily involved in the placenta, not the brain.